Guangzhou East is located at Dongzhan Road, Tianhe District. It has a front square and a main building. The front square has three levels: a pedestrian path on overhead level, an automobile path on ground level, and bus stations and metro stations at underground level. The main building has four floors. The ground floor has waiting hall for the Guangzhou-Shenzhen line. There are ticket office selling tickets to Hong Kong and Shenzhen. Ticket vending machines for Guangzhou-Shenzhen line are also there. Second floor has VIP restrooms and long-haul train ticket offices. Third floor has ticket offices, check-in points, and waiting halls. The fourth floor is the Guangzhou-Hong Kong railway check-in point. The station operates train type D, K and T.
Guangzhou East Coach Station is nearby Guangzhou East Railway Station. There are coaches to Shenzhen, Dongguan, Zhongshan, Zhuhai, Foshan, Qingyuan, Jiangmen, Zengcheng, Huadu etc.